The goal of this clinical trial is to evaluate the safety, tolerability, and pharmacokinetic (PK) profile of FHND1002 granules in healthy adult volunteers. The study will also assess how a high-fat meal affects the PK characteristics of FHND1002. The main questions this study aims to answer are: What are the safety and tolerability of FHND1002 granules when administered as single or multiple doses? What are the PK parameters of FHND1002, and what metabolites can be identified in humans? Participants will: Take FHND1002 granules or a placebo once daily, either as a single dose or for 7 consecutive days. Attend regular clinic visits for checkups, tests, and blood sample collection. Undergo assessments, including monitoring for adverse events, physical exams, vital signs, ECGs, and laboratory tests.
Age range
18 Years – 45 Years
Sex
ALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Peak Plasma Concentration (Cmax)
Timeframe: 4 weeks
Time to Peak Plasma Concentration (Tmax)
Timeframe: 4 weeks
Area Under the Curve from 0 to the Last Quantifiable Time Point (AUClast)
Timeframe: 4 weeks
Area Under the Curve Over the Dosing Interval (AUCτ)
Timeframe: 4 weeks
Trough Concentration (Cmin)
Timeframe: 4 weeks
Average Plasma Concentration (Cavg)
Timeframe: 4 weeks
Accumulation Ratio (Rac)
Timeframe: 4 weeks
Elimination Half-life (t1/2)
Timeframe: 4 weeks
Area Under the Curve from 0 to Infinity (AUC0-inf)
Timeframe: 4 weeks
Incidence of Adverse Events(AEs)
Timeframe: 7 weeks
Incidence of Adverse Drug Reactions (ADRs)
Timeframe: 7 weeks