RecruitingNot Applicable

Combining Light Therapy and CPAP in Depression

France130 participantsStarted 2025-01-17

Plain-language summary

In a double-blind, parallel-group controlled trial, we aim to measure the effect of two weeks of light therapy combined with the CPAP on compliance CPAP in patients with major depressive disorder.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adults consulting at the MICHEL JOUVET unit, CH Le Vinatier, Bron * Adults with a diagnosis of major depressive episode (DSM-V) and with a MADRS score ≥ 15 * Adults with a diagnosis of OSAS on ventilatory polygraphy or polysomnography (AASM 2017 criteria) requiring CPAP. Exclusion Criteria: * Refusal to participate. * Pregnant and breast-feeding women * Under guardianship or curatorship. * Unstable psychiatric or physical pathology (e.g., hypomania, high suicidal risk) considered incompatible with the study by the investigators. * Other psychiatric, neurologic or somatic conditions * Contraindication to light therapy: retinopathy, retinitis pigmentosa, diabetic retinopathy, macular degeneration, glaucoma, recent eye surgery (less than 3 months). patient wishing to choose a provider other than the protocol provider. * Patient wishing to choose a device other than SEFAM's S-BOX or a mask other than the nasal mask at the time of introduction. * Nasal obstruction. * Refusal to use actimetry, refusal to use light therapy, refusal to use CPAP.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

CPAP Compliance

Timeframe: 1 time :Day 14

Trial details

NCT IDNCT06781593

SponsorHôpital le Vinatier

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-10-30

Contact for this trial

Sébastien S CATOIRE, Dr

+330437915495 sebastien.catoire@ch-le-vinatier.fr

View on ClinicalTrials.gov More Major Depression trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.