Brain Stimulation for Foot-sole Sensation in Older Adults With Foot-sole Somatosensory Deficits (NCT06771531) | Clinical Trial Compass
RecruitingNot Applicable
Brain Stimulation for Foot-sole Sensation in Older Adults With Foot-sole Somatosensory Deficits
United States20 participantsStarted 2026-02-26
Plain-language summary
In older adults, diminished sensation of the legs and feet is highly prevalent and causes poor balance and reduced mobility. This type of sensation is not only dependent upon the receptors and nerves in the legs and feet, but also upon a complex central nervous system pathway that includes the cerebral cortex of the brain. This project will use a form of noninvasive brain stimulation called transcranial direct current stimulation (tDCS) to test whether increasing the excitability of the brain networks that process sensory feedback can augment foot sole sensation, balance, and mobility in older adults suffering from mild-to-moderate foot sole sensory impairments.
Who can participate
Age range65 Years
SexALL
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Inclusion criteria
✓. Aged ≥65 years.
✓. Self-reported feeling of unsteadiness or difficulty when standing and walking.
✓. Mild-to-moderate foot-sole somatosensory impairment: the ability to perceive 75g monofilament but inability to perceive 10g monofilament.
Exclusion criteria
✕. self-reported inability to stand or walk continuously for one minute without personal assistance (canes or walkers allowed);
✕. history or presence of foot ulceration, amputation, or deformities;
✕. self-reported uncontrolled pain or pain that is associated with mobility disability;
✕. uncontrolled diabetes mellitus;
✕. hospitalization within the past three months due to acute illness, or as the result of a musculoskeletal injury significantly affecting balance;
✕. persistent severe pain of lower extremity when standing or walking;
What they're measuring
1
postural sway area when standing with eyes closed on the foam
Timeframe: Before and immediately after intervention
2
Timed Up-and-Go (TUG) time
Timeframe: Before and immediately after intervention
3
On-target Blood oxygen level dependent (BOLD) signal intensity in response to foot sole stimulation
Timeframe: Before and immediately after intervention
4
Standing vibratory thresholds of each foot sole
Timeframe: Before and immediately after intervention