Efficacy of La Roche Posay Routine in the Management of Facial Post Inflammatory Hyperpigmentatio… (NCT06770127) | Clinical Trial Compass
CompletedNot Applicable
Efficacy of La Roche Posay Routine in the Management of Facial Post Inflammatory Hyperpigmentation (PIHP)
Mauritius80 participantsStarted 2023-02-27
Plain-language summary
The goal of this clinical trial is to test and compare La Roche Posay routine --the studied product-- with a comparator product in participants with acne. The main question it aims to answer is how well can the product de-pigment the skin.
The participants will be asked to use the products given twice daily. Researchers will compare the routine La Roche Posay group(experimental) with the routine Eucine group(control) to see if the La Roche product shows superiority in case of better efficacy.
Who can participate
Age range18 Years – 50 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Fitzpatrick skin phototype: III to VI;
* Moderate to severe PIHP due to acne (score PAHPI \> 10);
* Subjects with mild acne on the face (GEA = 2);
* ≤ 4 inflammatory lesions total (non-inflammatory lesions could be 0)
Exclusion Criteria:
* Subjects with symptoms of COVID-19 (moderate fever, dry cough and other symptoms described by the World Health Organization);
* Subjects with a temperature above 37.5 °C;
* COVID-19 positive patients;
* For women: pregnant or nursing woman or woman planning to get pregnant during the study;
* Cutaneous pathology on the study zone (eczema, etc);
* Use of topical or systemic treatment (for ex: treatment of acne) during the previous weeks liable to interfere with the assessment of the cutaneous acceptability/efficacy of the study product;
* Subject with make-up products on the day of the visit at the laboratory;
* Acne and depigmenting treatment (topical or systemic):
* Topical treatment claiming depigmenting effect of the face: within the last month,
* Facial procedures: within the last 3 months,
* Systemic retinoid: within the last 6 months.
* Cosmetic product for non-comedogenicity within the last 2 weeks;
* Subjects treated for PIHP within the past 3 months with either a cosmetic product or a drug;
* Any change in hormonal treatment (including contraceptive) during the three previous months of the study;
* Subject having undergone a surgery under general anesthesia within the previous month;
* Excessive exposure to…
What they're measuring
1
Clinical scoring of the post-acne hyperpigmentation index