CompletedNot Applicable

Efficacy of La Roche Posay Routine in the Management of Facial Post Inflammatory Hyperpigmentation (PIHP)

Mauritius80 participantsStarted 2023-02-27

Plain-language summary

The goal of this clinical trial is to test and compare La Roche Posay routine --the studied product-- with a comparator product in participants with acne. The main question it aims to answer is how well can the product de-pigment the skin. The participants will be asked to use the products given twice daily. Researchers will compare the routine La Roche Posay group(experimental) with the routine Eucine group(control) to see if the La Roche product shows superiority in case of better efficacy.

Who can participate

Age range

18 Years – 50 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Fitzpatrick skin phototype: III to VI; * Moderate to severe PIHP due to acne (score PAHPI \> 10); * Subjects with mild acne on the face (GEA = 2); * ≤ 4 inflammatory lesions total (non-inflammatory lesions could be 0) Exclusion Criteria: * Subjects with symptoms of COVID-19 (moderate fever, dry cough and other symptoms described by the World Health Organization); * Subjects with a temperature above 37.5 °C; * COVID-19 positive patients; * For women: pregnant or nursing woman or woman planning to get pregnant during the study; * Cutaneous pathology on the study zone (eczema, etc); * Use of topical or systemic treatment (for ex: treatment of acne) during the previous weeks liable to interfere with the assessment of the cutaneous acceptability/efficacy of the study product; * Subject with make-up products on the day of the visit at the laboratory; * Acne and depigmenting treatment (topical or systemic): * Topical treatment claiming depigmenting effect of the face: within the last month, * Facial procedures: within the last 3 months, * Systemic retinoid: within the last 6 months. * Cosmetic product for non-comedogenicity within the last 2 weeks; * Subjects treated for PIHP within the past 3 months with either a cosmetic product or a drug; * Any change in hormonal treatment (including contraceptive) during the three previous months of the study; * Subject having undergone a surgery under general anesthesia within the previous month; * Excessive exposure to…

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Clinical scoring of the post-acne hyperpigmentation index

Timeframe: 84 days

Trial details

NCT IDNCT06770127

SponsorCosmetique Active International

Sponsor typeINDUSTRY

Study typeOBSERVATIONAL

Primary completion2023-10-16

View on ClinicalTrials.gov More Acne trials