Clinical Evaluation and Study of the Efficacy of a Centella Asiatica-Infused Facial Mask on Disco… (NCT06763367) | Clinical Trial Compass
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Clinical Evaluation and Study of the Efficacy of a Centella Asiatica-Infused Facial Mask on Discosmetic Dermatosis
China30 participantsStarted 2025-01-08
Plain-language summary
The purpose of this study was to investigate the efficacy and safety of repairing facial mask containing Asiaticum asiatica in treating disjunctive skin diseases. A multi-center randomized double-blind self-half face control method was used. A computer-generated randomization method was used. Each cheek was randomly assigned to receive the snow glycoside mask and the control group.
Who can participate
Age range18 Years – 60 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Meet mild to moderate rosacea, acne diagnostic criteria; Meet the diagnostic criteria for melasma;
✓. Over 18 years of age;
✓. Be able to follow the treatment rules of the study and be followed for 8 weeks;
✓. Informed consent; 5There were no significant cardiac, liver, kidney, gastrointestinal, neurological, psychiatric, or metabolic disorders
✓.No medication was used within 1 month
Exclusion criteria
✕. Currently pregnant, planning to become pregnant or breastfeeding;
✕. Documented hypersensitivity to any active ingredient or excipient included in the study drug, or a history of adverse reactions to cosmetic products;
✕. Participate in other clinical studies within 3 months before the start of the study;
✕. Frequent use of Chinese medicine, sleeping pills, sedatives, anti-anxiety drugs or potentially addictive substances;
✕. Present with concomitant skin conditions that may confuse the clinical assessment of rosacea, melasma, seborrheic dermatitis or pose a risk to participants, or have a history of severe skin conditions;
✕. Normal use of relevant treatment (including intense pulsed light, pulsed fuel laser, oral and topical tranexamic acid, oral tetracycline antibiotics, oral compound glycyrrhizin and other anti-inflammatory drugs)
What they're measuring
1
Clinical erythema Score (CEA)
Timeframe: Patients were followed up on the day of treatment and at 1, 2, 3, 4, 6, and 8 weeks after treatment.
2
Global Aesthetic Improvement Scale Score (GAIS)
Timeframe: Patients were followed up on the day of treatment and at 1, 2, 3, 4, 6, and 8 weeks after treatment.
3
Melasma Area and Severity Rating (MASI)
Timeframe: Patients were followed up on the day of treatment and at 1, 2, 3, 4, 6, and 8 weeks after treatment.
Trial details
NCT IDNCT06763367
SponsorNanjing First Hospital, Nanjing Medical University