Hormonal Control of Energy and Macronutrient Intake in Obesity (MEMORY) (NCT06752967) | Clinical Trial Compass
RecruitingNot Applicable
Hormonal Control of Energy and Macronutrient Intake in Obesity (MEMORY)
Denmark45 participantsStarted 2024-12-12
Plain-language summary
The overall aim of the MEMORY study is to examine the concept of 'food memory' - how specific macronutrient compositions influence subsequent food preference and intake, and whether this differs across the BMI range from normal weight to obesity.
Who can participate
Age range18 Years – 45 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 18-45 years
* For women: Regular menstruation
* BMI-range 18.5-39.9 kg/m\^2
Exclusion Criteria:
* Not able or willing to eat or drink the test meals because of e.g., allergy or intolerance
* Daily smoking
* For women: Pregnancy / planned pregnancy (within the study period) / lactating
* Self-reported history of an eating disorder
* Self-reported weight change (kg) within two months prior to inclusion
* HbA1c ≥48 mmol/mol
* Treatment with antidepressants
* Alcohol/drug abuse or in treatment with disulfiram (antabus) at time of inclusion
* Uncontrolled medical issues including but not limited to cardiovascular pulmonary, rheumatologic, hematologic, oncologic, infectious, gastrointestinal, or psychiatric disease; diabetes or other endocrine disease; immunosuppression
* Current treatment with medication which significantly affect appetite or energy balance (e.g., GLP-1 receptor agonists)
* Bariatric surgery
* Unable to understand the informed consent and the study procedures
* Concomitant participation in intervention studies
* Participant's withdrawal of the informed consent
* Other safety concerns - judged by the investigator
What they're measuring
1
Difference in energy intake from sweet tasting carbohydrates.
Timeframe: Measured after meal consumption at t=150 min