CompletedNot Applicable

Evaluation of the Effect of a Probiotic in Patients Undergoing Orthodontic Therapy

Italy60 participantsStarted 2025-01-01

Plain-language summary

Orthodontic patients need supplementary oral hygiene tools in addition to professional oral hygiene. The aim of this study is to evaluate the effects of Bifidobacterium animalis subs. Lactis HN019 on plaque accumulation and gingival bleeding in orthodontic patients.

Who can participate

Age range10 Years – 30 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * age range of 10 to 30 years old; * good general health; * patients undergoing fixed multibracket orthodontic treatment; * patients undergoing invisible aligner orthodontic treatment. Exclusion Criteria: * physical, mental or motor disabilities; * systemic conditions that influence the progression of gingivitis; * presence of non-plaque-induced gingivitis; * known allergies; * smokers (if more than 5 cigarettes per day); * use of antibiotics, anti-inflammatories, or probiotics in the 6 months prior to recruitment.

What they're measuring

Full Mouth Bleeding Score (FMBS)

Timeframe: 4 months

Trial details

NCT IDNCT06752330

SponsorUniversity of Turin, Italy

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-06-30

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