CompletedNot Applicable

Changes in FeNO Value During Pulmonary Rehabilitation in Patients with Asthma

Germany62 participantsStarted 2021-05-17

Plain-language summary

This study investigates the use of fractional exhaled nitric oxide (FeNO) measurement to monitor non-pharmacological therapy during a three-week inpatient rehabilitation programme for asthma patients. It compares FeNO levels (measured three times a day) with clinical parameters and quality of life to analyse daily fluctuations and the acute effect of exercise training on FeNO levels. As FeNO is a non-invasive biomarker of airway inflammation, this study aims to expand its role in therapy monitoring and explore its application in a rehabilitation setting.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * confirmed diagnosis of bronchial asthma (all disease severities) * Chronic Obstructive Pulmonary Disease (COPD) with an asthma component, where the asthma component plays a clinically relevant role * written informed consent Exclusion Criteria: * Chronic Obstructive Pulmonary Disease (COPD) as the primary disease * unability to perform FeNO measurement independently

What they're measuring

Fractional Exhaled Nitric Oxide (FeNO) at rest

Timeframe: From enrollment to the end of rehabilitation at 3 weeks. Daily measurements at 9AM; 1PM; 5PM

Fractional Exhaled Nitric Oxide (FeNO) before/after exercise

Timeframe: From enrollment to the end of rehabilitation at 3 weeks, FeNO measurements will be done before and after a bicycle endurance training

Trial details

NCT IDNCT06751550

SponsorSchön Klinik Berchtesgadener Land

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-12-20

View on ClinicalTrials.gov More Asthma Bronchiale trials