Radiographic and Histological Assessment of GBR Using DBB Compared to Spontaneous Bone Regenerati… (NCT06749158) | Clinical Trial Compass
CompletedNot Applicable
Radiographic and Histological Assessment of GBR Using DBB Compared to Spontaneous Bone Regeneration of Maxillary Defects , Resulted From Enucleation of Intra-bony Cystic Lesions
Egypt44 participantsStarted 2024-12-30
Plain-language summary
Two groups of patients with maxillary defects resulted from enucleation of intra-bony cystic lesions the 1st group will be subjected to guided bone regeneration while the second group will be subjected to spontaneous bone regeneration.
Who can participate
Age range20 Years – 50 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Presence of a well-defined pathological cystic lesion involving the maxilla, confirmed clinically and radiographically that require surgical enucleation resulting in an intra-bony defect.
✓. Mesiodistal dimension of the defect ranging from 1 cm to 4.0 cm.
✓. Patients aged 20 to 50 years, of either sex.
✓. Patients medically fit for surgical intervention under local or general anesthesia (ASA I or II)
✓. Absence of systemic conditions affecting bone healing (e.g., uncontrolled diabetes, osteoporosis)
✓. Patients willing to participate in the study and able to provide informed written consent.
✓. Availability of adequate postoperative follow-up (minimum of 6 months).
Exclusion criteria
✕. Pregnant or lactating women.
✕. Radiographically, Presence of multi-locular or aggressive lesions suggestive of odontogenic tumors (e.g., ameloblastoma)
✕. Patients with compromised immune status (e.g., HIV, long-term corticosteroid therapy)
✕. History of allergic reaction to any of the surgical materials used (e.g., titanium, bovine bone graft).
✕. Patients participating in another clinical trial or receiving investigational therapy during the study period.