Efficacy of a Multidomain Intervention on Lifestyle Risk Factors for Dementia Prevention (NCT06748625) | Clinical Trial Compass
Active — Not RecruitingPhase 3
Efficacy of a Multidomain Intervention on Lifestyle Risk Factors for Dementia Prevention
Canada370 participantsStarted 2025-03-13
Plain-language summary
Alzheimer's Disease (AD) and other Dementias have far-reaching consequences on the lives of sufferers and their loved ones, not to mention the impact on the healthcare system. Several studies have identified protective lifestyle habits that might help reduce the risk of cognitive decline: cognitive engagement, physical activity, and a healthy diet. Our aim is to determine the efficacy of the Luci program, an online, coach-assisted, multidomain, behavioural intervention designed to help middle-aged to older adults reduce their risk of dementia by improving their lifestyle habits. In this study, we hope to demonstrate that participating in the Luci program helps to improve lifestyle habits and that the program could therefore become an effective health promotion tool.
Who can participate
Age range50 Years – 75 Years
SexALL
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Inclusion Criteria :
* Aged between 50 and 75;
* Proficient or native speakers in French or English;
* Computer literate defined as being able to read mails and browse the Internet, and having access to a computer or tablet with an Internet connection;
* Eligible in at least one of the 3 intervention domains, where eligibility is defined as follows:
* Low cognitive engagement in cognitively stimulating activities, defined as a score ≤ 22 on the adapted Cognitive Activity Questionnaire;
* Low level of physical activity defined as less than 150 minutes/week) of moderate to vigorous physical activity measured using the Godin- Shephard Leisure Time Physical Activity Questionnaire, and no medical contraindication to physical activity based on the Physical Readiness Questionnaire for Everyone (PAR-Q+);
* Low adherence to the Mediterranean-type diet defined as a score of ≤ 8 on the adapted Canadian Mediterranean Diet Scale, and no dietary restriction, severe allergy or intolerance or history of eating disorder.
Exclusion Criteria :
* Presence of a cognitive impairment as measured by the Creyos Dementia Assessment;
* General anesthesia within the last 6 months;
* Previous participation in the Luci program or in any validation studies related to the program;
* Current participation in another study;
* Unable to commit participation over the period of the study;
* Being in the precontemplation stage of change;
* High level of perceived stress;
* Having received a diagnosis of…