RecruitingPhase 4

Establishing Mobile Transcranial Magnetic Stimulation

United States30 participantsStarted 2025-05-10

Plain-language summary

In this pilot study, investigators propose to design and create a portable TMS unit, in a van, and then test out delivering TMS in three different locations in South Carolina, all affiliated with MUSC and within 2-hours driving from Charleston, SC. This study would test out this new delivery mode, and provide valuable feasibility, safety, and efficacy lessons for later refinement and potential widespread adoption of mobile TMS as a treatment option, both in our state and across the US.

Who can participate

Age range22 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult (22-80 years old) * Have treatment-resistant depression as defined by the e-Mini, and the antidepressant treatment history form (ATHF short). * Be able to read and communicate in English. * Able to provide their own consent. * Access to a computer with videoconferencing ability for initial consent and telescreen. Exclusion Criteria: * Patients with unstable medical conditions that might make TMS unsafe. This includes current poorly controlled seizures. * Ferromagnetic metal in the head. * Pregnant. * Currently active substance abuse except tobacco.

What they're measuring

Percent of depression responders

Timeframe: From baseline to 1 week immediately after treatment week

Improvement in Depression Symptoms

Timeframe: From baseline to 1 week immediately after treatment week

Trial details

NCT IDNCT06748209

SponsorMedical University of South Carolina

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-03-01

Contact for this trial

Mark S George, MD

8438765142 GEORGEM@MUSC.EDU

View on ClinicalTrials.gov More Treatment Resistant Major Depression trials