Pilot Study of ELK-003 Eye Drops for Treating Ocular Manifestations of Epidermolysis Bullosa

Inclusion Criteria: * Confirmed diagnosis of Recessive Dystrophic and Junctional Epidermolysis bullosa * Frequent history of corneal abrasions (one or more abrasions every 3 months) * Age: older than 2 years at the time of joining the clinical trial * Patients and/or parent/legal guardian has given written informed consent in writing Exclusion Criteria: * Acute eye infection at time of enrollment * Patients with severe vision loss (\<20/200) or severe corneal opacification. * Contact lens wear or nocturnal eye ointment * Hypersensitivity to fluorescein (ocular stain used in slit lamp study) * History of alcohol abuse or drug addiction * Patient who reports difficulty to attend the 4 in-person controls * Patients who are suffering from cancer * Patients with any medical condition or situation which in the opinion of the investigators could put the patient at risk, or could interfere with the patient's participation in the study * Pregnant or breastfeeding women (a pregnancy test will be performed using a urine sample for female patients who have had menarche).