CompletedPhase 2/3

The Effect of Vitamin D3 Supplementation on Hepcidin and Ferritin Serum Levels in Children With Chronic Kidney Disease

Indonesia43 participantsStarted 2023-05-01

Plain-language summary

The goal of this clinical trial is to analyze the effects of in vitamin D3 on serum hepcidin and ferritin levels among children with chronic kidney disease. The main questions it aims to answer is: "What is the effect of giving vitamin D3 on serum hepcidin and ferritin levels in children with chronic kidney disease?" We will compare the effect of vitamin D3 administration on hepcidin and ferritin between 2 groups. Group A consists of children with GFR more 90 mL/min/1,73 m2. Group B consists of children with GFR less than 90 mL/min/1,73 m2 Participants will be given the same 2000 IU of Vitamin D/day for 6 weeks.

Who can participate

Age range2 Years – 18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients aged 2 to 18 years diagnosed with chronic kidney diseases at Dr. Wahidin Sudirohusodo hospital * Parents have signed their child's consent to participate in the study Exclusion Criteria: * History of blood transfusion 3 months prior * Liver dysfunction * Sepsis * Routine consumption of Vitamin D * Routine consumption of iron supplement * Patients diagnosed with iron deficiency anemia

What they're measuring

Vitamin D Level

Timeframe: From enrollment to the end of treatment at 6 weeks

Ferritin Level

Timeframe: From enrollment to the end of treatment at 6 weeks

Hepcidin level

Timeframe: From enrollment to the end of treatment at 6 weeks

Trial details

NCT IDNCT06706271

SponsorHasanuddin University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-08-01

View on ClinicalTrials.gov More Chronic Kidney Disease Stage 1 trials