The goal of this study is to assess the value of liver dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and texture analysis post gadopiclenol for liver fibrosis staging, in comparison with MR elastography, T1 mapping, ultrasound elastography and blood tests in 50 initial patients with metabolic dysfunction-associated steatohepatitis (MASH).
Who can participate
Age range18 Years – 89 Years
SexALL
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Inclusion Criteria:
* Patients with suspected MASLD (F0-F4) with clinically indicated percutaneous or transjugular liver biopsy within 6 months of MRI (before or after MRI).
* Both genders.
* Age \> 18 years.
* Any racial/ethnic background.
Exclusion criteria:
* Previous history or current diagnosis of HCC or decompensation.
* Contraindications for MRI, including
* Medically unstable
* Intracranial clips
* Metal implants
* Suspected or confirmed metal in eyes
* Cardiac pacemaker, implanted defibrillator, other implanted electronic device
* Pregnancy: Pregnancy tests will be offered to women of childbearing age at no cost
* Severe claustrophobia