Treatment of Post Traumatic Knee Osteoarthritis With Extracorporeal Shockwave Therapy (NCT06686680) | Clinical Trial Compass
RecruitingNot Applicable
Treatment of Post Traumatic Knee Osteoarthritis With Extracorporeal Shockwave Therapy
United States70 participantsStarted 2025-04-01
Plain-language summary
This study is recruiting current or former athletes who had ACL reconstruction surgery over a year ago and have been diagnosed with knee osteoarthritis (OA). We are doing the research to investigate the effects of extracorporeal shockwave therapy (ESWT) on pain, function, biomechanics, knee range of motion and strength, inflammation, and joint structure and integrity of the knee.
Who can participate
Age range18 Years – 55 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Previous ACL reconstruction using an autograft or allograft in the knee with PTOA
* Minimum of one year following ACL reconstruction surgery
* Between ages of 18 and 55
* No clear contraindication to complete protocol including mechanical symptoms which would limit ability to complete the study
* Score on KOOS for 2 of 4 domains (pain, symptoms, activities of daily living (ADL), quality of life (QOL)) of 85 or lower
* Primary pain is coming from the knee
* Diagnosis of PTOA based on clinical diagnosis and confirmation with radiographic evidence by a medical professional prior to study enrollment. If individuals have suspected OA based on impairments such as pain, they must have a score on KOOS for 2 of 4 domains (pain, symptoms, activities of daily living (ADL), quality of life (QOL)) of 85 or lower to participate in the study.
Exclusion Criteria:
* Have previously received injections to the knee joint within the past 3 months
* Women who are pregnant or those who are planning to become pregnant. This is due to the fact that pregnancy will reduce participants activity after the treatment and the safety concerns related to shockwave treatment. - Participants with neuropathy affecting sensation to pain
* Participants with a known underlying cardiac disease that could be affected by shockwave therapy
* Chronic rheumatological conditions, immunodeficiency, severe asthma, connective tissue disorder (i.e. Ehlers-Danlos Syndrome), or other medical conditions…
What they're measuring
1
Knee Injury and Osteoarthritis Outcome Score (KOOS)
Timeframe: From baseline to 4-month follow up with intermediate measure at 8 weeks