Active — Not RecruitingPhase 2

Clinical and Radiographic Evaluation of Propolis As a Hemostatic Agent for Pulpotomy of Mature Permanent Molars with Irreversible Pulpitis Using Two Different Dressing Materials

Egypt60 participantsStarted 2024-11-01

Plain-language summary

The goal of this clinical trial is to assess the effectiveness of propolis as a hemostatic agent in pulpotomy for adult permanent molars, compared to sodium hypochlorite (NaOCl). It also examines how bioceramic putty performs against mineral trioxide aggregate (MTA) in vital pulp therapy for cases of irreversible pulpitis. Participants will be divided into four groups (15 patients each): * Propolis + bioceramic putty * Propolis + MTA * Sodium hypochlorite + bioceramic putty * Sodium hypochlorite + MTA The Investigator will record the bleeding time and postoperative pain will be recorded. The researcher will assess the clinical and radiographic outcomes for success at 1, 3, and 6 months.

Who can participate

Age range20 Years – 45 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Participants of both genders falling within the age range of 20 to 45 years. * Presence of vital mature permanent molars diagnosed as mild or severe irreversible pulpitis per Wolter's classification. * Confirmation of vital bleeding pulp tissue in all canals following complete pulpotomy. Exclusion Criteria: * Non-vital teeth. * Teeth with Immature roots. * Uncontrolled pulpal bleeding persisting beyond 10 minutes post-application of sodium hypochlorite as a hemostatic agent. * Insufficient bleeding post-pulp exposure, indicative of pulp degeneration.

What they're measuring

Clinical and radiographic success rate

Timeframe: 1, 3, 6 months

Bleeding time

Timeframe: During hemostasis (0-10 minutes)

Trial details

NCT IDNCT06679075

SponsorMisr International University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-08