The goal of this clinical trial is to learn more about mood, sleep, and activity during menopause. The main question it aims to answer is: can mood and sleep dysfunction in menopause be improved by resetting misaligned circadian rhythm through one night of strategic sleep timing adjustment and two weeks of exposure to bright light at a certain time of day? Researchers will compare sleep timing (earlier vs. later) and bright white light exposure (morning or evening) to investigate the effect of melatonin levels on mood, sleep, and activity. Participants will 1) submit urine samples to measure melatonin levels, 2) be assigned to advance or delay their sleep for one night, 3) sit in front of a light box for 30 minutes per day (morning or evening) for 14 days, 4) complete questionnaires about their mood and sleep, and 5) wear a device that will measure their activity.
Age range
18 Years
Sex
FEMALE
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Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Urine-based 6-sulfatoxymelatonin (6-SMT)
Timeframe: Baseline and after completing two-week intervention.
Structured Interview Guide for the Hamilton Rating Depression Scale with Atypical Depression Supplement (SIGH-ADS)
Timeframe: Baseline and after completing two-week intervention; sustained at two weeks post intervention completion through three months post intervention completion.
Patient Health Questionnaire (PHQ-9)
Timeframe: Baseline and after completing two-week intervention; sustained at two weeks post intervention completion through three months post intervention completion.
Sleep Quality Rating (SQR)
Timeframe: Baseline and after completing two-week intervention; sustained at two weeks post intervention completion through three months post intervention completion.
Objective Measures of Sleep
Timeframe: Continuous monitoring from one week prior to baseline through one week post intervention completion.
Objective Measures of Physical Activity
Timeframe: Continuous monitoring from one week prior to baseline through one week post intervention completion.