Active — Not RecruitingNot Applicable

EFFECTS OF OLEUROPEIN ON BLOOD PARAMETERS AND INFLAMMATORY MARKERS IN ADULTS WITH METABOLIC SYNDROME

Turkey (Türkiye)34 participantsStarted 2024-11-01

Plain-language summary

The aim of this study is to determine the effect of 6 weeks supplementation of oleuropein on individuals diagnosed with metabolic syndrome. The baseline and end biochemical parameters and anthropometric measurements will be compared with control subjects.

Who can participate

Age range

18 Years – 49 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Individuals who volunteer to participate in the study by signing the voluntary consent form * Diagnosed with Metabolic Syndrome * Individuals who did not have any infection at the time the study started * Not consuming any medication * Not pregnant or lactating * Women aged 18-49 who have not entered menopause and men in the same age group * Willing to consume the given extract * Not allergic or intolerant to olive leaves * No history of drug use * People with a BMI below 40 kg/m2 Exclusion Criteria: * The patient included in the study leaves the study * Any health issues that may affect the results of the research during the research. * Occurrence of the problem and/or infection * Becoming pregnant during the research * Being in the experimental group and not consuming extract regularly * Failure to comply with the regulated medical nutrition treatment * Failure to participate in routine meetings and failure to complete necessary measurements * Starting to use any medication or nutritional supplement during the study * Leaving study voluntarily

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change from Baseline in the Fasting Blood Glucose (mg/dl) at 6 weeks

Timeframe: 6 weeks

Change from Baseline in the Insulin (uU/mL) at 6 weeks

Timeframe: 6 weeks

Change from Baseline in the Triglyceride (TG) (mg/dl), high density lipoprotein (HDL-C) (mg/dl), low density lipoprotein (LDL-C) (mg/dl), Total Cholesterol (mg/dl) at 6 weeks

Timeframe: 6 weeks

Change from Baseline in the HOMA-IR at 6 weeks

Timeframe: 6 weeks

Change from Baseline in the BMI (kg/m2)

Timeframe: 6 weeks

Change from Baseline in the Anthropometric Measurements

Timeframe: 6 weeks

Trial details

NCT IDNCT06673914

SponsorAtlas University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-12-30

View on ClinicalTrials.gov More Metabolic Syndrome trials

Who can participate

Age range

18 Years – 49 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change from Baseline in the Fasting Blood Glucose (mg/dl) at 6 weeks

Timeframe: 6 weeks

Change from Baseline in the Insulin (uU/mL) at 6 weeks

Timeframe: 6 weeks

Change from Baseline in the Triglyceride (TG) (mg/dl), high density lipoprotein (HDL-C) (mg/dl), low density lipoprotein (LDL-C) (mg/dl), Total Cholesterol (mg/dl) at 6 weeks

Timeframe: 6 weeks

Change from Baseline in the HOMA-IR at 6 weeks

Timeframe: 6 weeks

Change from Baseline in the BMI (kg/m2)

Timeframe: 6 weeks

Change from Baseline in the Anthropometric Measurements

Timeframe: 6 weeks