This comparison examines the effectiveness of povidone-iodine and chlorhexidine in managing iatrogenic wounds in surgical patients. Both antiseptics are commonly used to prevent postoperative infections, but they differ in mechanism, efficacy, and safety profiles. Povidone-iodine releases iodine, which acts broadly against bacteria, viruses, and fungi, while chlorhexidine disrupts cell membranes, providing rapid bactericidal action. Studies suggest that chlorhexidine may offer longer-lasting antibacterial effects, but povidone-iodine has a wider antimicrobial range. Optimal choice depends on patient needs, wound type, and potential for adverse reactions, emphasizing the need for tailored antiseptic strategies in wound care.
Age range
18 Years – 45 Years
Sex
ALL
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A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Numerical Rating Scale (NRS)
Timeframe: Up to twelve weeks
EuroQol-5D (EQ-5D)
Timeframe: Up to twelve weeks
Patient Satisfaction Questionnaire (PSQ)
Timeframe: Up to twelve weeks
Wound Healing Assessment Tool
Timeframe: Up to twelve weeks
Adverse Event Reporting Form
Timeframe: Up to twelve weeks