Bacillus Coagulans Effect on Gastrointestinal Function in Healthy Adults.

Exclusion criteria

• ✕. Subjects aged \<18 or \> 65 years, pregnant or lactating women, and those who are susceptible to allergens or have food allergies.
• ✕. Subjects with cardiovascular, cerebrovascular, hepatic, renal, hematopoietic diseases or endocrine diseases, and or mental illness.
• ✕. Subjects with constipation symptoms caused by surgical operation within the past 30 days; subjects with acute GI track diseases in the past 30 days; subjects with constipation symptoms due to severe organ lesion (colon cancer, severe enteritis, intestinal obstruction, inflammatory bowel disease, etc.)
• ✕. Subjects who could not eat orally or take the study products as prescribed or cannot comply with the protocol.
• ✕. Subjects administered relevant products recently, which would affect the outcome of the study.
• ✕. Subjects who took probiotics or prebiotics products (including yogurt, beverages or foods containing probiotics) within the past month, which may affect the results of the study.
• ✕. Subjects who suffered from gastrointestinal disease within the past month.
• ✕. Subjects who had taken antibiotics in the past month.