CompletedNot Applicable

FILIP: Fat Intake, Inflammation and LIPids

Sweden25 participantsStarted 2025-04-08

Plain-language summary

Low-grade inflammation is involved in the pathogenesis of type 2 diabetes and cardiovascular disease. Increasing evidence suggests that dietary intake may be involved in the inflammatory process. How nutritional composition of the diet affects the inflammatory response is however not well understood. The aim of this project is to study if intake of three different fat sources induce different effects on inflammation markers, blood lipids, blood glucose and the microbiota.

Who can participate

Age range18 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 18-60 * Willing to eat the study diet Exclusion Criteria: * malabsorption-related condition * contraindications to consume a high fat diet * intolerance to any foods used in the study (e.g. cow's milk, egg, gluten) * established cardiovascular disease, diabetes or cancer * current use of medication known to affect lipid metabolism (e.g. statins) or inflammation (e.g. NSAID, glucocorticoids). * hemoglobin \<100 g/L * ongoing pregnancy or lactation

What they're measuring

Total cholesterol

Timeframe: Baseline and 1 week

hs-CRP

Timeframe: Baseline and 1 week

Trial details

NCT IDNCT06640036

SponsorGöteborg University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-12-17

View on ClinicalTrials.gov More Cardiometabolic Risk Factors trials