Hemophilia is a rare X-linked congenital bleeding disorder characterized by deficiency of clotting factor VIII (hemophilia A) or deficiency of factor IX (hemophilia B) with complex diagnosis and management. Participation in physical activity is still limited in children with hemophilia, probably due to protective attitudes of families/patients and avoidance of activity, and possibly also as a result of chronic pain. Exercise capacity has been identified as a protective factor against joint problems in hemophilia. Aerobic fitness is associated with better pulmonary function in children. Chronic pain and decreased range of motion due to recurrent bleeding in joints and muscles in hemophilia may indirectly affect posture and respiratory mechanics, leading to impaired pulmonary function. This study aims to compare pulmonary function, exercise capacity, posture, and physical activity level between children with hemophilia and healthy controls and to investigate the relationship between these parameters.
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Forced vital capacity
Timeframe: 1st day
Forced expiratory volume in one second
Timeframe: 1st day
Forced expiratory volume in one second/forced vital capacity ratio
Timeframe: 1st day
Peak expiratory flow
Timeframe: 1st day
Forced mid-expiratory flow (FEF25-75)
Timeframe: 1st day
Hemophilia Joint Health Score
Timeframe: 1st day
Corbin Posture Rating Scale
Timeframe: 1st day
Exercise capacity
Timeframe: 1st day
Physical activity level
Timeframe: 1st day