Impact of Reactogenicity of the 2024-2025 COVID-19 Vaccines on Health Care Workers and First Responders in the United States

Inclusion Criteria: * Adults aged 18 years and older who have received at least one COVID-19 vaccination in the past 4 years * Health care workers or first responders who have direct face-to-face contact, defined as being within 3 feet, or about an arm's length, with patients as part of their full-time or part-time (greater than or equal to 20 hours per week) job responsibilities * Intends to receive a dose of the updated 2024-25 COVID-19 vaccine * Able to understand and provide informed consent * Comfortable reading and responding to text messages and emails sent in English or having an interpreter assist them * Able and willing to comply with all study requirements * Access to a smartphone, tablet, or computer to complete the consent, screener and study questionnaires Exclusion Criteria: * Ongoing participation in other vaccine or investigational product trials within 90 days of study enrollment * History of self-reported severe allergic reaction to prior COVID-19 vaccine * Receipt of COVID-19 vaccine within 60 days of enrollment * Plans to receive additional vaccines within 7 days after the vaccination visit for study enrollment. (Co-administered vaccinations at time or day of COVID-19 vaccination are permissible)