Task-oriented Training on Hand Function in Taxanes-induced Peripheral Neuropathy (NCT06632626) | Clinical Trial Compass
CompletedNot Applicable
Task-oriented Training on Hand Function in Taxanes-induced Peripheral Neuropathy
Egypt60 participantsStarted 2023-09-01
Plain-language summary
Chemotherapy based on taxanes is commonly used to treat breast cancer. However, chemotherapy-induced peripheral neuropathy (CIPN), a side effect of taxanes, impairs a patient's grip strength, hand dexterity, and upper extremity function which affects quality of life (QOL).
Who can participate
Age range
35 Years – 65 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients were females only.
* Their ages range from 35 to 65.
* All patients suffered from CIPN after using taxanes (anti-cancer agent causing neurotoxic effect).
* Diagnosis of CIPN was determined based on symptom history or the presence of stocking glove pattern "distal dysesthesias, pain and numbness" beginning after taxanes intake.
* All patients enrolled to the study had their informed consent.
* Patients suffer from affected brachial plexus.
Exclusion Criteria:
* Patients had pain or numbness in the upper extremity due to other reasons like trauma (fracture), CNS diseases (cerebral infarction), other diseases with neurological symptoms like (diabetes, rheumatoid arthritis or cervical myelopathy).
* Patients had bone, brain or spinal cord metastases.
* Patients who had history of psychiatric disorders like: depression and schizophrenia or cognitive decline that may hinder them from active participation in the study.
* Patients exhibited only acute neuropathy like in patients using oxaliplatin.
Exclusion Criteria:
* Patients had pain or numbness in the upper extremity due to other reasons like trauma (fracture), CNS diseases (cerebral infarction), other diseases with neurological symptoms like (diabetes, rheumatoid arthritis or cervical myelopathy).
* Patients had bone, brain or spinal cord metastases.
* Patients who had history of psychiatric disorders like: depression and schizophrenia or cognitive decline that may hinder them from active part…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Hand grip strength
Timeframe: At baseline and after four weeks of intervention.
2
Hand dexterity
Timeframe: At baseline and after four weeks of intervention.
3
Hand function
Timeframe: At baseline and after four weeks of intervention.