Levothyroxine (T4) is a man-made thyroid hormone used to treat certain thyroid conditions. After taking levothyroxine, a person's body changes it to triiodothyronine (T3). The amount of levothyroxine in a person's blood must be carefully controlled to maintain proper function. Enlicitide decanoate was designed to lower the amount of cholesterol in a person's blood. Researchers want to learn about levothyroxine when taken at the same time with enlicitide decanoate. They want to: * Measure a person's blood to find out if the amount of levothyroxine in the blood is the same when levothyroxine is taken alone or with enlicitide decanoate * Learn about the safety of levothyroxine when taken alone or with enlicitide decanoate and if people tolerate it
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Area under the Concentration-Time Curve from Time 0 to 48 hours (AUC0-48hrs) of Levothyroxine (total T4)
Timeframe: At designated timepoints (up to approximately 48 hours postdose)
Maximum Plasma Concentration (Cmax) of Levothyroxine (total T4)
Timeframe: At designated timepoints (up to approximately 48 hours postdose)
Time to Maximum Plasma Concentration (Tmax) of Levothyroxine (total T4)
Timeframe: At designated timepoints (up to approximately 48 hours postdose)
Area under the Concentration-Time Curve from Time 0 to 48 hours (AUC0-48hrs) of Triiodothyronine (total T3)
Timeframe: At designated timepoints (up to approximately 48 hours postdose)
Maximum Plasma Concentration (Cmax) of Triiodothyronine (total T3)
Timeframe: At designated timepoints (up to approximately 48 hours postdose)
Time to Maximum Plasma Concentration (Tmax) of Triiodothyronine (total T3)
Timeframe: At designated timepoints (up to approximately 48 hours postdose)