Acute Effect of Capsimax on Resistance Exercise Performance, Muscle Oxygenation, Nitric Oxide Rel… (NCT06612658) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Acute Effect of Capsimax on Resistance Exercise Performance, Muscle Oxygenation, Nitric Oxide Release, Resting Energy Expenditure and Reaction Time
United States40 participantsStarted 2024-10-01
Plain-language summary
Capsimax is a novel, proprietary encapsulated form of capsaicin, a natural and bioactive phytochemical found in chili pepper and other spicy food. The purpose of this study is to investigate the effect of Capsimax on resistance exercise performance, reaction time, and resting energy expenditure around exercise. This investigation will also measure muscle oxygenation and intramuscular nitric oxide in real time during resistance exercise using a non-invasive wearable technology.
Primary Objective • To examine the effects of Capsimax on physical performance metrics including peak power and rate of force development during an isometric strength test and performance during the barbell back squat exercise protocol (e.g., repetitions performed, total volume, peak power, average power).
Secondary Objectives
* To examine the effects of Capsimax on resting energy expenditure around exercise.
* To examine the effects of Capsimax on nitric oxide bioavailability and skeletal muscle oxygenation during exercise.
Exploratory Objective
• To examine the effects of Capsimax on reaction time around exercise
Who can participate
Age range18 Years – 35 Years
SexMALE
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Inclusion criteria
✓. Male subjects aged between 18-35 years (both limits inclusive).
✓. Subjects must have a BMI of 18.5 to 29.9 kg/m2 (both limits inclusive)
✓. Subjects must have greater than one year of resistance training experience at a frequency of 2 days per week.
✓. Subjects must be proficient in the barbell back squat exercise.
✓. Subjects must be free of any physical limitations or chronic illness that may affect performance.
✓. Subjects must be free of any medications.
✓. Subjects who agree to refrain from consuming alcohol 24 hours prior to the visit days.
✓. Subjects who agreed to refrain from consuming caffeine and caffeine-containing products 12 hour prior to visit days
Exclusion criteria
✕. Subjects who have hypersensitivity or history of allergy to the study product.