CompletedPhase 1

Effects of Microtox on Facial Skin Quality, Fine Wrinkles, and Texture

United States20 participantsStarted 2024-09-03

Plain-language summary

The goal of this split-face clinical trial is to test the efficacy of microtox in improving facial skin quality, fine wrinkles, and texture. Participants will: * be randomly assigned to Group A (which will receive 20 units of neuromodulator on the left side of the forehead and a placebo saline treatment on the right side) or Group B (which will receive 20 units of neuromodulator on the left side of the forehead and 20 units of a different neuromodulator brand on the right side as a comparator) * have one treatment session at week 0, and two live assessment visits at weeks 2 and 12 * have their pictures taken at each visit to track progress

Who can participate

Age range

18 Years – 65 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Biological females, 18-65 years old, of any race and ethnic background * Individuals with mild to moderate facial wrinkles * All skin types (Fitzpatrick I-VI) * Willingness to participate and provide written informed consent * Ability to follow study instructions and likely to complete all required visits Exclusion Criteria: * Females who are pregnant, breastfeeding, chronically using nonsteroidal anti-inflammatory drugs, have autoimmune conditions or have a known allergy to the study medications. * Previous cosmetic procedures near the forehead within the last 6 months or botulinum toxin treatments within the last 4 months * Known neuromuscular disorders or a hypersensitivity to botulinum toxin * Significant dermatological conditions affecting the face * Use of medications affecting neuromuscular function or skin healing within 2 weeks prior to the beginning of study * Subject has a condition or is in a situation which, in the opinion of the Investigator, may put the subject at significant risk, may confound the study results, or may interfere significantly with participation in the study.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Scientific Assessment Scale of Skin Quality (SASSQ) Rating

Timeframe: Up to 12 weeks

Global Aesthetic Improvement Scale (GAIS) Rating

Timeframe: Up to 12 weeks

Trial details

NCT IDNCT06604832

SponsorKalpna Kay Durairaj, MD, FACS

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-08-29

View on ClinicalTrials.gov More Skin Aging trials