Propofol-related Euphoria in Pain-free Gastrointestinal Endoscopy Patients

Inclusion Criteria: * Proposed to perform painless GI endoscopy, and simple endoscopic maneuvers such as single small polyp clamping, performing HP examination, etc; * Gender is not limited; * 18 years old ≤ 80 years old; * ASA classification: I-II; * 18 kg/m2 \<BMI \<30 kg/m2; * Informed consent, voluntary participation in the trial, and informed consent signed by the subjects themselves. Exclusion Criteria: * adjudicated respiratory management difficulties; * History of substance abuse as well as drug use; * Participation in a clinical trial of another drug or device within 3 months prior to the screening period * Use of therapeutic drugs (e.g., benzodiazepines, opioid analgesics) by the subject within 3 months prior to the Screening Period for a variety of reasons (e.g., insomnia, pain, etc.) that may have an impact on the outcome of the trial, etc; * Allergy or contraindication to the study drug or components thereof; * Previous psychiatric or neurological disorders (e.g., schizophrenia, mania, bipolar disorder, psychosis, epilepsy, neuralgia, etc.) and a history of taking medications corresponding to the treatment of the corresponding psychiatric or neurological disorders (e.g., antidepressants, anxiolytics, convulsants, antiepileptic drugs, etc.); * Pregnant women; * Subjects with severe communication disorders due to severe hearing deterioration; * Refusal to participate in this study; * Those deemed unsuitable by the investigator.