RecruitingNot Applicable

Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease

United States25 participantsStarted 2025-10-23

Plain-language summary

Adolescents and young adults with sickle cell disease (SCD) face challenges managing their illness and maintaining their well-being. This study proposes to test the feasibility and acceptability of a resilience-promoting intervention through a Collaborative Care Model. The primary goal is to determine with the resilience intervention (PRISM) is feasible and acceptable for adolescents and young adults with SCD. Exploratory outcomes include whether this intervention improves depression, anxiety, and pain interference.

Who can participate

Age range8 Years – 25 Years

SexALL

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Inclusion Criteria: * Aged ≥ 8 and ≤ 25 years of age at baseline * Diagnosed with Sickle Cell Disease (HbSS, HbSC, HbS-Beta Thalassemia, and other related hemoglobinopathies) * Receiving Medical Care at the DFCI/BCH Blood Disorders Center. * Scored \> 9 on Patient Health Questionnaire 9-item (PHQ-9) or Generalized Anxiety Disorder (GAD) * Able to speak English or Spanish language (for PRISM sessions) * Able to read English or Spanish language (for completion of surveys) * Cognitively able to participate in PRISM sessions and complete written questionnaires and surveys, as judged by the site investigator * Willing and able to adhere to the study visit schedule and other protocol requirements Exclusion Criteria: \* does not meet above criteria

What they're measuring

Enrollment rate (feasibility)

Timeframe: 3-months

Trial details

NCT IDNCT06555939

SponsorBoston Children's Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2029-09

Contact for this trial

Abby Rosenberg, MD

617.632.5286 abbyr_rosenberg@dfci.harvard.edu

View on ClinicalTrials.gov More Sickle Cell Disease trials