Topical 1% Methotrexate Gel Versus Clobetasol Propionate in Patients With Psoriasis

Inclusion Criteria: * patients with stable mild-moderate plaque psoriasis, regardless of chronicity of the disease, * involving less than 30% of the body surface area (BSA) * negative pregnancy test for female participants of reproductive age Exclusion Criteria: * patients with psoriatic lesions on the face and/or scalp, * administration of topical, systemic, or intralesional therapy or UV radiation therapy for at least 2 weeks before the study. * Patients with deranged laboratory results at the baseline of the study, minors or lactating mothers * patients planning a pregnancy with their spouses/partners in the next three months.