Single Lipiflow Treatment to Reduce Pharmacologic Burden in DED (NCT06542276) | Clinical Trial Compass
By InvitationNot Applicable
Single Lipiflow Treatment to Reduce Pharmacologic Burden in DED
United States30 participantsStarted 2023-09-01
Plain-language summary
Purpose: To evaluate the efficacy of vectored thermal pulsation treatment in subjects with a history of dry eye disease currently using a topical immunomodulator medication.
Who can participate
Age range
25 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* No prior history of meibomian gland treatment procedures LipiFlow, TearCare, or I-Lux
* lifitegrast or cyclosporine eye drops daily for a period of at least one year but not exceeding five years
* Meibograpy documneted retention of at least 50% of meibomian glands.
Exclusion Criteria:
* evidence of meibomian gland dropout exceeding 50%
* ocular rosacea,
* ocular surgery within the preceding three months
* prior in-office thermal meibomian gland treatment
* ocular trauma within preceding three months
* ocular herpetic infection
* chronic or recurrent inflammation
* eyelid abnormalities affecting lid function ocular surface abnormalities compromising corneal integrity (eg, epithelial basement membrane dystrophy, corneal burn)
* pregnant
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Number of Subjects discontinuing Topical Immunomodulator use