Studying the Effect of Ethanol Applied on the Corneal Surface During PRK Surgery. (NCT06540131) | Clinical Trial Compass
CompletedNot Applicable
Studying the Effect of Ethanol Applied on the Corneal Surface During PRK Surgery.
Egypt70 participantsStarted 2024-03-05
Plain-language summary
The goal of this observational study is to learn about the effects of the duration of ethanol contact with the corneal surface. The main question it aims to answer is: Does this affect the behavior of corneal epithelial healing?
Who can participate
Age range18 Years – 45 Years
SexALL
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Inclusion Criteria:
* The included patients should meet the following criteria: age between 18 and 35 years, both genders, with normal corneal topography, clear cornea, and stable refractive error for at least 12 months before the surgery. Both eyes should have low to moderate myopia with spherical error of more than -4D spherical error, cylindrical error of more than -1.5D, and an estimated stromal ablation depth of less than 70 µm.
Exclusion Criteria:
* The patients were excluded from the study if they had one or more of the following findings: patients with mixed astigmatism in either eye, contact lens wearers, abnormal corneal topography, thin cornea less than 500 microns, corneal opacity, dry eye disease, history of herpetic keratitis, corneal epithelial pathology (dystrophies or scarring), atopy, collagen diseases, autoimmune disease, systemic diseases that interfere with healing (e.g. diabetes mellitus), eyelid diseases, ocular pathology, previous history of refractive or corneal surgery, and pregnant or lactating females. Also, patients who failed to attend the follow-up visits were excluded.
What they're measuring
1
epithelial healing
Timeframe: The patients were folllowed daily upto 2 weeks