Identification of Olfactory Biomarkers of Skin Cancer From Skin Odor Samples: a Pilot Study (NCT06493786) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Identification of Olfactory Biomarkers of Skin Cancer From Skin Odor Samples: a Pilot Study
120 participantsStarted 2024-07-25
Plain-language summary
The aim of this research is to determine which volatile organic compounds (odors) are associated with different skin cancers.
To this end, odor samples will be taken from various parts of the body, from patients with skin cancers and from "healthy" subjects who have no skin cancer.
The various samples collected will be analyzed in the laboratory, and compared with each other, to determine whether there is a specific "smell" for the main types of skin cancer.
Who can participate
Age range18 Years
SexALL
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Inclusion criteria
✓. Adult patient (age ≥ 18 years),
✓. Patient with a diagnosis of skin cancer of the malignant melanoma, basal cell carcinoma or squamous cell carcinoma type, established by in vivo imaging of the confocal microscopy or LC-OCT type, more than 24 hours old (definitive confirmation being made by anatomopathological examination of the postoperative excision specimen),
✓. Patient with a lesion located on a flat surface measuring at least 3 cm by 2 cm,
✓. Patient who has not applied any cosmetic products, such as deodorant, perfume, perfumed cream or soap, or hair care products, in the 24 hours prior to sampling,
✓. Patient who has not handled odorous substances (e.g. household products, paints) in the 24 hours prior to sampling,
✓. Patient who has not eaten a meal (or flavored substances such as drinks or sweets) within 2 hours of sampling,
✓. Patient able to read, understand and give documented informed consent,
✓. Patient willing and able to comply with protocol requirements for the duration of the study,
Exclusion criteria
✕. Patient or subject who has expressed opposition to participation in the study,
✕. Patient or subject under guardianship, deprived of liberty, under psychiatric care or hospitalized in a health or social institution,
✕. Patient or subject linguistically unable to understand the terms of the study,
What they're measuring
1
Comparison of chromatographic profiles of skin VOCs
Timeframe: 12 months
Trial details
NCT IDNCT06493786
SponsorAssociation pour la Recherche Clinique et Immunologique