Prucalopride for Cognitive Functioning in Schizophrenia

Inclusion Criteria: * Diagnosed as schizophrenia by DSM 5 criteria using Structured Clinical Interview for DSM disorders * Age between 18 to 55 years * A minimum of one year of duration of illness * Clinically stable with a stable therapeutic dose for at least 3 months prior to the recruitment * Participants who can read and write English or Kannada Exclusion Criteria: * Participants who are acutely symptomatic and are uncooperative for assessments * Co morbid with other psychiatric illness including mood disorders and substance use disorders except tobacco * Participants already diagnosed with Intellectual Disability Disorder, head injury * Participants administered MECT (modified electroconvulsive therapy) * Participants with sensory impairments * Use of Donepezil, Rivastigmine, Memantine, Benzodiazepines * Participants already on prucalopride * Participants with contraindications to prucalopride * Diagnosed with gastrointestinal disorders like Ulcerative colitis, Crohn's disease, Intestinal ulcers * Use of concomitant herbal remedies, alternative medicines * Women who are pregnant or lactating * Current history of suicidal ideation, intention or attempts