Verification of the Efficacy/Safety of the Mixed Drug Injectable Delivery Vehicle for Treating Intractable Hearing Loss

Inclusion Criteria: * Patients with sudden hearing loss, Meniere's disease, ototoxic hearing loss, and noise-induced hearing loss of 25dB HL at the frequency at which hearing loss occurs as a result of pure tone hearing test * Patients whose original hearing ability has not been restored with existing standard treatment (oral, intravenous steroids) * Those who have not participated in clinical trials within 3 months are selected as subjects Exclusion Criteria: * Pregnant or lactating women * When accompanied by lesion, infection, or anatomical deformity of the outer ear, middle ear, or inner ear * Those with liver disease or metabolic disease or a history thereof * History of hypersensitivity to indocyanine green or iodine hypersensitivity * History of ear surgery * Cases with posterior labyrinth lesions * Patients with a history of hypersensitivity to the ingredients of this drug * In addition, serious diseases such as end-stage renal disease, end-stage liver disease, cardiovascular surgery, progressive brain tumor, progressive hemorrhage, and progressive cerebral hemorrhage are included Cases with brain disease and cancer are excluded from the study