Exploring the Relationship Between Heart Rate Variability (HRV), Training Load, and Exercise Perf… (NCT06425939) | Clinical Trial Compass
CompletedNot Applicable
Exploring the Relationship Between Heart Rate Variability (HRV), Training Load, and Exercise Performance
United States49 participantsStarted 2024-05-08
Plain-language summary
Heart rate variability (HRV) is a measure of the variation in time between each heartbeat.
It is an indirect and ubiquitous biomarker of performance readiness and recovery measured by most consumer-grade wearable fitness trackers. However, there is little documented on the relationship between HRV, training load, and performance measures in the Real-World.
Whoop wrist-worn activity trackers have been validated against the gold-standard Electrocardiography (ECG) for HRV and HR measurements. Whoop leverages photoplethysmography (PPG) technology to continuously track (HR, HRV, respiratory rate, energy expenditure) and provides, daily, individual insights, trends, and coaching to improve strain, sleep, and recovery. Research has demonstrated that heart rate variability (HRV) guided training may be more optimal compared to predetermined training for aerobic exercise improvements.
The purpose of this study is to assess the feasibility of providing personalized training recommendations based on HRV measured by a consumer-grade wearable (Whoop) in a real-world setting to better understand the HRV relationship with performance.
Who can participate
Age range
25 Years – 50 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Actively participating in resistance training 2-4 times per week.
. Age 21-50 years, male and female.
. Subject is willing to refrain from vigorous exercise (light physical activity only) 24 hours prior to visit(s).
. Subject is willing to avoid alcohol consumption 24 hours prior to visit(s).
. Subject is willing to provide consent.
. Subject is able to continuously wear a wrist-worn device, including during sleep, except when submerged underwater (i.e., swimming, bathing).
Exclusion criteria
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Training Intensity
Timeframe: Change from baseline (Day 1) to mid-study (Day 45) and end of study (Day 90)
2
Performance
Timeframe: Change from baseline (Day 1) to mid-study (Day 45) and end of study (Day 90)
3
Peak Power Output
Timeframe: Change from baseline (Day 1) to mid-study (Day 45) and end of study (Day 90)
4
Jump Height
Timeframe: Change from baseline (Day1) to mid-study (Day 45) and end of study (Day 90)
5
Dynamic Push Ups Peak Force
Timeframe: Change from baseline (Day 1) to mid-study (Day 45) and end of study (Day 90)
. Individual has a condition the Investigator believes would interfere with his ability to provide informed consent, comply with the project/study protocol, which might confound the interpretation of the project/study results or put the person at undue risk.
. Those with a medical history that would interfere with the results of this study.
. Under the care of a physician.
. Skin sensitivities.
. Sleep disorders.
. Using prescription medications that would impact sleep.
. If female, you are not pregnant, planning to get pregnant or currently breast feeding.