Central venous (CVC) is essential in modern healthcare but unfortunately associated with complications, including thrombosis. In a recently published study, it was showed that 12 out of 12 deceased patients had subclinical CVK-related thrombosis (Rockholt et al.). To shed light on this problem, the current studies were designed. In sub-study 1, deceased patients with CVC who are referred for clinical autopsy are included. Before the autopsy, the deceased will be examined with a photon-counting computed tomography (CT) scan and the results will be compared. In sub-study 2, living patients with CVC who are referred for various CT scans without contrast, are included. After informed consent, the patient will be examined with the photon-counting CT, whose reliability has been validated in Part 1 and the incidence of subclinical CVC-related thrombosis will be reported.
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The incidence of venous thrombosis related to a central venous catheter in diseased patients
Timeframe: At autopsy
The performance of the photon counting CT on diseased patients
Timeframe: After death. The CT scan and the autopsy will be performed within 1 week after death
The incidence of venous thrombosis related to a central venous catheter in living patients
Timeframe: At CT scan
The performance of ultrasound compared to the photon counting CT
Timeframe: Ultrasound will be performed ±24 hours from the CT