CompletedNot Applicable

Role of NLRP6 in Chronic Periodontitis

Iran50 participantsStarted 2024-12-13

Plain-language summary

The quantification of NLRP6 in blood samples will be analyzed from individuals with chronic periodontitis but without systemic disease. Demographic and periodontal parameters will be assessed and correlated with the NLRP6 quantification using RT-PCR.

Who can participate

Age range25 Years – 79 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age: At least 25 years old * Clinical diagnosis of chronic periodontitis * At least 15 teeth in the mouth Exclusion Criteria: * premalignant lesions and cancer of the oral cavity * periodontal treatment in the last 6 months * systemic disorders affecting the periodontal condition (autoimmunity and endocrine disorders) * diabetes mellitus and rheumatoid arthritis * pregnancy or breastfeeding * taking drugs with the possibility of affecting the periodontal condition (calcium channel blockers, anticonvulsants, etc.) * Smoking * aggressive PD

What they're measuring

Quantification of NLRP6 gen, Quantification of NLRP6 gen using RT-PCR

Timeframe: 12 months

Trial details

NCT IDNCT06400069

SponsorBabol University of Medical Sciences

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-02-28

View on ClinicalTrials.gov More Chronic Periodontitis trials