Role of Sclerotherapy in Treatment of Non-neoplastic Ovarian Cyst (NCT06399744) | Clinical Trial Compass
CompletedNot Applicable
Role of Sclerotherapy in Treatment of Non-neoplastic Ovarian Cyst
Egypt52 participantsStarted 2022-09-01
Plain-language summary
The aim of this study was to evaluate the role of sclerotherapy (injection of tetracycline or injection of Polidocanol - 95% hydroxypolyethoxydodecane and 5% ethanol -) in treatment of non-neoplastic ovarian cysts by, percutaneous trans-abdominal approach or trans-vaginal approach.
Who can participate
Age range15 Years – 48 Years
SexFEMALE
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Inclusion Criteria:
* Patients were diagnosed with non-neoplastic ovarian cysts (i.e., simple, hemorrhagic, complicated, endometriotic cysts).
* All Patients from 15 to 48 years old.
* Size from (5 to 10 cm).
* Cyst wall thickness \< 5 mm.
* Negative tumor markers (Cancr Antigen125, Cancer Embryonic Antigen, Cancer Antigen19.9 \& alpha fetoprotein).
* Persisted for more than 3 months.
* Normal color Doppler blood flow analysis.
* Resistant to hormonal treatment COCs.
* Patients accepted to be enrolled in the study.
Exclusion Criteria:
* Family history of ovarian cancer.
* USG features suggesting malignancy like: multilocular, papillary projections or mural nodule, cyst wall thickness \>5mm, low Doppler indices (PI≤1 and or RI≤0.40, centrally located vessels, randomly dispersed vessels).
* Known allergy to sclerosing agent (tetracycline or Polidocanol).
* Bleeding tendency as (patients with platelet count \<50,000, patients with Uncorrected Coagulopathy with International Normalized Ratio \>1.5, or patients on antithrombotic therapy without stoppage of doses till 5 days before the procedure.
What they're measuring
1
role of sclerotherapy in treatment of non-neoplastic ovarian cysts