CompletedNot Applicable

Role of Sclerotherapy in Treatment of Non-neoplastic Ovarian Cyst

Egypt52 participantsStarted 2022-09-01

Plain-language summary

The aim of this study was to evaluate the role of sclerotherapy (injection of tetracycline or injection of Polidocanol - 95% hydroxypolyethoxydodecane and 5% ethanol -) in treatment of non-neoplastic ovarian cysts by, percutaneous trans-abdominal approach or trans-vaginal approach.

Who can participate

Age range

15 Years – 48 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients were diagnosed with non-neoplastic ovarian cysts (i.e., simple, hemorrhagic, complicated, endometriotic cysts). * All Patients from 15 to 48 years old. * Size from (5 to 10 cm). * Cyst wall thickness \< 5 mm. * Negative tumor markers (Cancr Antigen125, Cancer Embryonic Antigen, Cancer Antigen19.9 \& alpha fetoprotein). * Persisted for more than 3 months. * Normal color Doppler blood flow analysis. * Resistant to hormonal treatment COCs. * Patients accepted to be enrolled in the study. Exclusion Criteria: * Family history of ovarian cancer. * USG features suggesting malignancy like: multilocular, papillary projections or mural nodule, cyst wall thickness \>5mm, low Doppler indices (PI≤1 and or RI≤0.40, centrally located vessels, randomly dispersed vessels). * Known allergy to sclerosing agent (tetracycline or Polidocanol). * Bleeding tendency as (patients with platelet count \<50,000, patients with Uncorrected Coagulopathy with International Normalized Ratio \>1.5, or patients on antithrombotic therapy without stoppage of doses till 5 days before the procedure.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

role of sclerotherapy in treatment of non-neoplastic ovarian cysts

Timeframe: followed up from 1 month to 6 months

Trial details

NCT IDNCT06399744

SponsorAl-Azhar University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-01-30

View on ClinicalTrials.gov More Benign Ovarian Cyst trials