Decreasing Nightmares in Adults With Narcolepsy (NCT06383806) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Decreasing Nightmares in Adults With Narcolepsy
United States80 participantsStarted 2026-04-01
Plain-language summary
The purpose of this clinical trial is learn whether a behavioral (non-medication) treatment can reduce nightmares in adults with narcolepsy. All participants will receive the treatment and will complete three assessments. Half of the participants will receive the treatment after the first assessment, and half will receive it after the second assessment. Romantic partners of participants with narcolepsy will also be eligible to enroll in the study. Partners will complete three assessments but will not participate in the treatment.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
PARTICIPANTS WITH NARCOLEPSY/NIGHTMARES
Inclusion Criteria:
* Diagnosis of narcolepsy type 1 or narcolepsy type 2
* Nightmare frequency of ≥1 times per week
* Age 18 or older
* Able to speak, read, and write in English
* Live in the United States
* Sleep and psychiatric medications stable for ≥ 1 month and willing to keep medications stable for the duration of the study
Exclusion Criteria:
* Currently engaged in trauma- or sleep-related psychotherapy
* Previous behavioral treatment for nightmares
* Medical, psychiatric, or cognitive condition which would interfere with ability to engage in the treatment
* Untreated moderate-severe sleep apnea
PARTICIPANTS WHO ARE PARTNERS OF SOMEONE WITH NARCOLEPSY
Inclusion Criteria:
* Live with a romantic partner who meets the above criteria and has agreed to participate in the study
* Age 18 or older
* Able to speak, read, and write in English
* Live in the United States
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Disturbing Dream and Nightmare Severity Index (DDNSI)
Timeframe: Completed at each of the three assessments (baseline, 10 weeks, 19 weeks)
2
Nightmare frequency (sleep diary)
Timeframe: Completed at each of the three assessments (baseline, 10 weeks, 19 weeks)