Clinical Evaluation of Polycation-based New Dental Desensitizer on Dentin Hypersensitivity (NCT06378255) | Clinical Trial Compass
CompletedNot Applicable
Clinical Evaluation of Polycation-based New Dental Desensitizer on Dentin Hypersensitivity
China40 participantsStarted 2024-03-20
Plain-language summary
Evaluate the safety and clinical efficacy of new dental desensitizers in the treatment of dentin sensitivity, including the relief of sensitivity symptoms and the duration of efficacy.
Who can participate
Age range18 Years – 70 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Dentin Hypersensitivity, with Vas score≥4 points and the normal pulp viability
* dentin-sensitive tooth in at least 2 different quadrants of the mouth (neck enamel dentin exposure or maxillofacial abrasion within the middle layer of dentin).
* in good overall health
* participants informed consent.
Exclusion Criteria:
* gastroesophageal reflux
* Dental caries, wedge defects, crowns or large fillings.
* Received dentin sensitivity desensitization treatment or used desensitization mouthwash within 1 month.
* Received systematic periodontal therapy or periodontal surgery within 3 months, ongoing orthodontic treatment, and medical treatment, including long-term use of anti-inflammatory, analgesic, and psychotropic medications.
* Pregnancy or breastfeeding.
* Participated in other clinical trials in the past 3 months.
What they're measuring
1
Improvement of dentin sensitivity induced by probe pressure stimulation
Timeframe: At Baseline and 10 minutes, 1 month, 3 months, 6 months after desensitization treatment