A Study to Evaluate the Adjustment Function of a Modified Spatz3 Adjustable Balloon (Spatz4).

Inclusion Criteria: * Have a BMI ≥ 27; * Be male or female, between 18 and 65 years of age, inclusive; * Have a history of excess weight (BMI ≥ 27 kg/m2) for at least 2 years and have failed more conservative weight-reduction alternatives, such as supervised diet, exercise and behavioral modification programs; * Be willing to commit to a long-term low calorie (1000-1500 calories/day) supervised diet; * Have reasonable weight loss expectations (accept a goal of losing up to 15% of body weight after 52 weeks); * Be able to follow requirements outlined in the protocol, including complying with the visit schedule and behavioral modification program, and willing to undergo protocol-specific procedures, e.g., endoscopy, local sedation, general anesthesia, upper gastrointestinal radiography (UGI), electrocardiography (EKG), gastric motility testing, and/or clinical laboratory testing, and must be willing to take prescribed proton pump inhibitors (PPIs); * Be able to provide written informed consent; * Have successful completion of the pre-placement screening and educational programs supporting that the subject is an appropriate study candidate; * Be willing to use contraception (e.g., birth control pills, condoms, abstinence) and avoid pregnancy during the study if female of child-bearing potential. Exclusion Criteria: * Previous history of esophageal, gastric or duodenal surgery, any bariatric surgery, any hiatal hernia surgery, bowel obstruction surgery, adhesive peritonitis, a…