Clinical Study of the Effectiveness, Tolerability and Safety of the Drug "Anti-spike, Gel, 100 g in Bottles in Package No. 1" Produced by the Republican Unitary Enterprise "Unitekhprom BSU", With a Single Intraperitoneal Use After Surgery in Adult Patients With Acute Phlegmonous Appendicitis

Inclusion Criteria: * Presence of acute phlegmonous appendicitis requiring surgical intervention. * Presence of medium or high risk factor for the development of adhesions of the abdominal cavity; * Age of patients from 18 to 65 years. * Absence of severe concomitant diseases in decompensation stage, oncologic diseases, as well as diseases requiring steroid therapy. * Presence of written informed consent of the patient to participate in the study. * The patient's ability to fulfill the instructions of the research physician and comply with the study design. Exclusion Criteria: * At the subject own request without explaining the reasons for the behavior. * At the request of the physician-researcher if the subject violates the requirements of the protocol in terms of diet, smoking, consumption of alcoholic beverages, and use of medications without the prescription of the physician-researcher. * For reasons independent of the subject and the research physician, if the subject has drug intolerance or other life-threatening or life-threatening adverse reactions to drug administration that require emergency pharmacotherapy.