Caffeine and Cataract After Pars Plana Vitrectomy

Inclusion Criteria: * Age 18 or older * Written informed consent * No previous cataract surgery in the study eye * Scheduled small gauge vitrectomy with intraoperative gas tamponade (SF6 or C3F8) due to retinal detachment or macular hole repair * No regular caffeine consumption (drinking not more than one cup of a caffeine- containing beverage \[e.g. coffee, energy drinks\] at a maximum of two days per week during the past year) Exclusion Criteria: * Intake of systemic or topical corticosteroids within 3 months before study screening * Increased risk for postoperative cataract development, for example due to ocular trauma in the history * Severe cataract (LOCS III grading of any cataract form \>2) in the study eye at pre- study screening * Scheduled phacovitrectomy in the study eye * Participation in any clinical trial three month before study screening * Ocular surgeries six month before study screening