NRM on Vascular Perfusion in Healthy Adults (NCT06345443) | Clinical Trial Compass
By InvitationNot Applicable
NRM on Vascular Perfusion in Healthy Adults
United States200 participantsStarted 2024-11-25
Plain-language summary
The purpose of this study is to better understand the effects of nicotinamide riboside supplement in overall cardiovascular health in healthy adults.
Who can participate
Age range35 Years – 70 Years
SexALL
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Inclusion Criteria:
* \>= 35 and \<=70
* Provides consent to participate in the study
* Not pregnant at time of consent
* Understands and agrees to follow all study procedures and limitations
* Have no contraindicating comorbid health condition as determined by the clinical investigators
Exclusion Criteria:
* Pregnant, nursing, or trying to conceive
* BMI Restrictions: \<35
* Allergy or sensitivity to study agent ingredients
* Hypertension treated with medication
* Use of natural health products containing nicotinamide riboside, quercetin, trans-resveratrol, or betaine anhydrous within 7 days prior to randomization and during the course of the study.
* Surgery planned during the course of the trial
* History or past diagnosis of chronic diseases, unstable medical conditions, blood/bleeding disorders or stroke
* History or current diagnosis of cancer (except for successfully treated basal cell carcinoma diagnosed less than 5 years prior to screening or cancer in full remission more than 5 years after diagnosis.
* Abnormal blood chemistries for renal or liver function (defined as 1 standard deviation outside of the normal range), alcohol dependence, uncontrolled thyroid disease, severe obesity (body mass index \>40 kg m-2), or weight stable for at least 3 months prior to enrolling in the study (defined as \>2 kg change in body mass).
* An unstable medical or mental health condition as determined by the physician investigator.
What they're measuring
1
Number of Participants with Reduced Endothelial Stiffness