This is an open-label, dose escalation, multi-center, Phase I/II clinical trial to assess the safety of an autologous T-cell therapy (EB103) and to determine the Recommended Phase II Dose (RP2D) in adult subjects (≥ 18 years of age) who have relapsed/refractory (R/R) B-cell NHL. The study will include a dose escalation phase followed by an expansion phase.
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
To assess the Dose Limiting Toxicities of EB103.
Timeframe: Time Frame: 28 days
Incidence rates of Treatment-Emergent Adverse Events of EB103.
Timeframe: Time Frame: 90 days
Incidence rates Treatment-Emergent Laboratory Abnormalities reported for EB103.
Timeframe: Time Frame: 90 days
To determine the Recommended Phase II Dose (RP2D) of EB103.
Timeframe: Time Frame: 21 months