Heart failure (HF) is a global, public health issue that affects more than 63 million people worldwide; this burden is expected to increase substantially as the population ages. Despite advancements in treatment, a HF diagnosis still leads to significant morbidity and mortality; there is also an immense impact on patients' health-related quality of life (HRQoL). Dapagliflozin was recently granted approval for heart failure by the European Commission, regardless of ejection fraction and whether the patient has diabetes. Real-world observational data are necessary to describe dapagliflozin use in real-world settings in order to assess treatment patterns, HF symptoms and their impact on physical limitation, HRQoL and work productivity, as well as health care utilization of patients treated with dapagliflozin in this setting under local treatment standard conditions in Germany.
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Time to discontinuation of dapagliflozin
Timeframe: Baseline to 12 months
Reasons for discontinuation of dapagliflozin
Timeframe: Baseline to 12 months
Dose changes of dapagliflozin
Timeframe: Baseline to 12 months
Number of patients with dapagliflozin treatment interruptions
Timeframe: Baseline to 12 month
Treatment switches from dapagliflozin to other SGLT2i
Timeframe: Baseline to 12 months
Time to other heart failure treatment discontinuation
Timeframe: Baseline to 12 months
Number of other heart failure treatment initiation
Timeframe: Baseline to 12 months
Number of other heart failure treatment dosage changes
Timeframe: Baseline to 12 months
Number of other heart failure treatment discontinuation
Timeframe: Baseline to 12 months
Number of glucose lowering medication initiation
Timeframe: Baseline to 12 months
Number of glucose lowering medication dosage changes
Timeframe: Baseline to 12 months
Number of glucose lowering medication discontinuation
Timeframe: Baseline to 12 months