First-In-Human Study of PDT to Detect IAH

Inclusion Criteria: * Patient volunteer planning for laparoscopic surgery * Subjects willing to sign an informed consent form (ICF), * Adult subjects, age ≥ 20 and age ≤ 80 years old * BMI between 15（kg/m2）- 35（kg/m2） * Subjects willing to comply to study protocol requirements (blood pressure measurement, diet, alcohol, study visits, blood sampling, etc.) * Patient who had been scheduled for any laparoscopic surgery which may alter intra-abdominal pressure. * Patient volunteer planning for laparoscopic surgery, as self-declared and confirmed by screening assessments and Principal Investigator's judgment Exclusion Criteria: * Patients with a high risk for capsule retention (such as intestinal diverticula, acute abdominal pain without regular defecation indicating intestinal obstruction or a history of abdominal operation or intestinal reconstructed operation), * Any evidence that occlusion of gastrointestinal tract is obvious or severe paralytic ileus that may result in intra-abdominal hypertension in need of immediate surgical intervention not caused by base of tongue (i.e., central apnea, neurologic disorder, retropalatal collapse, nasal obstruction) * Any condition that subject is expected to undergo MRI examination within 7 days after ingestion of the capsule. * Any factor that, in the surgeon's judgment, would pose a risk to surgery or placement of an intra-gastrointestinal monitoring device * Any factor that, in the surgeon's judgment, would make the subject unlikely …