CompletedNot Applicable

The Effect of Over Weight on Oocytes Quality in IVF Patients

Israel50 participantsStarted 2022-02-01

Plain-language summary

Obesity is an increasing worldwide problem and a risk factor for many diseases. The effect of obesity on female fertility has been extensively tested. Obese women have increased time to pregnancy and remain subfertile even in the absence of ovulatory dysfunction. They present with higher incidence of infertility compared to normal weight women. This study is prospective observational cohort study performed between February 2022 until June 2022 in a single university-affiliated hospital.

Who can participate

Age range18 Years – 50 Years

SexFEMALE

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Inclusion criteria

✓. All women divided by BMI below 25 and above 25 who underwent IVF-ICSI treatment.
✓. Consent to participate in the study.

Exclusion criteria

✕. Patients older than 40 years
✕. Fertility preservation
✕. Unbalanced endocrine disorders
✕. Less than 4 follicles at the time of oocyte pick-up

What they're measuring

Impact of obesity on oocyte's mtDNA expression in Cumulus Cells

Timeframe: 6 months

Impact of obesity on oocyte quality through levels of protein BMP-15

Timeframe: 6 months

Impact of obesity on oocyte quality through levels of protein HSPG2

Timeframe: 6 months

Trial details

NCT IDNCT06331481

SponsorHillel Yaffe Medical Center

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2025-01-07

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