TADCLOT- a Double Blind Randomized Controlled Trial

Inclusion Criteria: * ST-segment elevation ≥1 mm in ≥ 2 contiguous ECG leads or New or presumably New left bundle branch block * Age ≥18 years * Written informed consent Exclusion Criteria: * Patients with STEMI secondary to stent thrombosis or index event being a complication of PCI within 30 days * Thrombolytic therapy \<24 hours * Platelet count \< 100,000 and Hemoglobin \<10 gm/dl * Pregnancy or lactation * Moderate to severe hepatic impairment * Patients with advanced CKD and those on hemodialysis * Recent ICH or major bleed requiring transfusion * Inability to give informed consent * Participation in another study * Inability to fulfill protocol (living outside the city etc.)